客户发表文献
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LncRNA SNHG6 attenuates ferroptosis in high glucose-treated renal tubular epithelial cells by stabilizing YY1 to activate the PI3K/AKT/GSK-3β pathway
Author:
Qiguo Wang, Qin Wang, Xiangyu Meng, Xiaoman Ji, Ting Wang
Journal: Archives of Biochemistry and Biophysics
Doi: https://www.doi.org/10.1016/j.abb.2025.110702
2025/12/11 -
A novel gene delivery platform based on a commensal human anellovirus demonstrates transduction in multiple tissue types
Author:
Cato Prince, George Bounoutas, Bolu Zhou, Waseem Raja, Isabella Gold, Riana Pozsgai, Parmi Thakker, Nicole Boisvert, Christopher Reardon, Stephanie Thurmond, Erin Ozturk, Rajendra Boggavarapu, Jenna Antonucci Johnson, Patricio Jeraldo, Simeon Springer, Lovepreet Chahal, Emily Stead, Cameron Dodier, Bryan Vought, Maciej Nogalski, Dhananjay Nawandar, Christopher Wright, Ashley Mackey, Geoffrey Parsons, Joseph Cabral
Journal: Molecular Therapy
Doi: https://www.doi.org/10.1016/j.omtm.2025.101597
2025/12/11 -
Base editing strategies for in vivo correction of two highly recurrent phenylketonuria variants
Author:
Aidan Quigley, Ishaan Jindal, Thomas Campion, Delaney Rutherford, Yongseok Han, Walsh Quigley, Ping Qu, Kiran Musunuru, Rebecca Ahrens-Nicklas, Xinying Hong, Xiao Wang
Journal: Molecular Therapy
Doi: https://www.doi.org/10.1016/j.omtn.2025.102770
2025/12/9 -
Anti–PD-L1–IFN-α–adjuvanted HBsAg vaccine overcomes HBV immune tolerance through targeting both DCs and macrophages
Author:
Chao-Yang Meng, Yong Liang, Longxin Xu, Hongjia Li, Jingya Guo, Hairong Xu, Fan Wang,Yang-Xin Fu, and Hua Peng
Journal: JCI insight
Doi: https://insight.jci.org/articles/view/198097
2025/12/8 -
Genome-Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle-Mediated siRNA Delivery
Author:
Wenhan Wang, Kangfu Chen, and Zongjie Wang
Journal: Advanced Science
Doi: https://www.doi.org/10.1002/advs.202517617
2025/12/7 -
Development of a high-affinity anti-ROR1 variable region for broad anti-cancer immunotherapy
Author:
Joshua K.M. Wong, Pui Yeng Lam, Elaina Coleborn, Jiya Jose, Louisa Alim , Cui Tu, Magdalena Antczak, Bettina Dietmair, Arghavan Golbaz Hagh, Lucia Noronha, Seth W. Cheetham, John Hooper, Paul A. Beavis, Delphine Merino, Jean Berthelet, Lauren G. Aoude, Amy E. McCart-Reed, Sunil Lakhani, Peter T. Simpson, Gustavo R. Rossi, Fernando Souza-Fonseca-Guimaraes
Journal: Molecular Therapy
Doi: https://www.doi.org/10.1016/j.ymthe.2025.11.021
2025/12/2 -
An RNA interference therapeutic potentially achieves functional cure of chronic hepatitis B virus infection
Author:
Ze-Ao Huang, Yang Yang, Shuo Yang, Guang-Shen Ji, Rui Fu, Zhi-Kang Tian, Yu-Cheng Wu & Geng-Shen Song
Journal: Nature Communications
Doi: https://www.doi.org/10.1038/s41467-025-66876-5
2025/12/1 -
BST2 impairs Schwann cell function to accelerate age-related hearing loss and serves as a novel serum biomarker
Author:
Mengxiao Liu, Huan Cao, Qi Li, Huan Yin, Jiantao Wang, Tao Liu, Lei Zhao, Jianwang Yang, Miaomiao An, Yanan Li, Chen Wang & Baoshan Wang
Journal: Acta Oto-Laryngologica
Doi: https://www.doi.org/10.1080/00016489.2025.2591707
2025/11/30 -
Activating PPARα in macrophages attenuates arterial remodeling via inhibiting YAP nuclear localization
Author:
Xinxin Lin, Xiaocong Liu, Jinglin shi, Tuohong Sun, Ting Feng, Benrui Sun, Hongbin Liang, Qiuxia Zhang, Guojun Chen, Siyu Chen, Alex Pui-Wai Lee, Shenjian Luo, Jiancheng Xiu, Xinlu Zhang
Journal: Biochemical Pharmacology
Doi: https://www.doi.org/10.1016/j.bcp.2025.117566
2025/11/28 -
Single-cell and bulk transcriptome analyses revealed the role of macrophage cholesterol metabolism in atherosclerosis
Author:
Jiaxing Ke, Shuling Chen, Lingjia Li, Chenxin Liao, Feng Peng, Dajun Chai & Jinxiu Lin
Journal: Lipids in Health and Disease
Doi: https://www.doi.org/10.1186/s12944-025-02773-6
2025/11/26 -
Single-nucleus RNA sequencing reveals GABAergic vulnerability and reactive gliosis driven by loss of TDP-43
Author:
Rashmi Thapa, Navin Adhikari, Sishir Gautam, Mingming Sun, Sierra McOmie, Viyaleta Davydzenka, Derek Smith, Jack Syring, Harlie Kaligis, Jade Marie Kosmicki, Rong Chen, Yun Li
Journal: iScience
Doi: https://www.doi.org/10.1016/j.isci.2025.113745
2025/11/21 -
Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity
Author:
Samuel J Resnick, Seema Qamar, Pushya Krishna, Vladislav Korobeynikov, Hannes Ausserwoger, Alyssa Miller, Pietro Esposito, Juan A Varela, Jenny Sheng, Lei Haley Huang, Jonathon Nixon-Abell, Schuyler Melore, Chyi Wei Chung, Nino F Läubli, Sofia Kapsiani, Xuecong Li, Jingshu Wang, Nancy Zhang, Mahabub Maraj Alam, Alondra S Burguete, Theresa C Swayne, Yanyan Chen, Ya-Cheng Liao, Neil A Shneider, Michele Vendruscolo, Tuomas P J Knowles, Clemens F Kaminski, Francesco Simone Ruggeri, Gabriele S Kaminski Schierle, Peter St George-Hyslop, Alejandro Chavez
Journal: Nat Commun
Doi: https://www.doi.org/10.1038/s41467-025-65178-0
2025/11/21