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Structural basis for the neurotropic AAV9 and the engineered AAVPHP.eB recognition with cellular receptors.
BioRxiv, 2022.  DOI:https://doi.org/10.1186/s13073-021-00876-0 
In vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers
Genome Medicine, 2021. DOI:https://doi.org/10.1186/s13073-021-00876-0 IF=10.675
Lineage tracing of direct astrocyte-to-neuron conversion in the mouse cortex.
Neural Regen Res 2021. DOI: 10.4103/1673-5374.295925 IF=3.171
Use of CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventricular delivery in mice.
Neural Regen Res 2021. DOI: https://doi.org/10.1038/s41434-021-00223-3 IF=4.128
CRISPR/Cas9 -Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I.
Molecular Therapy, 2021. DOI: https://doi.org/10.1016/j.ymthe.2020.11.023 IF=8.986
Hepatocyte-targeting and microenvironmentally responsive glycolipid-like polymer micelles for gene therapy of hepatitis B.
Molecular Therapy – Nucleic Acids 2021.DOI: https://doi.org/10.1016/j.omtn.2021.02.013 IF=7.032
Human ACE2‑Functionalized Gold “Virus‑Trap” Nanostructures for Accurate Capture of SARS‑CoV‑2 and Single‑Virus SERS Detection.
Nanomicro Lett. 2021. DOI: 10.1007/s40820-021-00620-8 IF=12.2645
Remdesivir Metabolite GS-441524 Effectively Inhibits SARS-CoV-2 Infection in Mouse Models.
J Med Chem. 2021. DOI: 10.1021/acs.jmedchem.0c01929 IF=6.205
Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9, Molecular Therapy.
J Med Chem. 2021. DOI: https:// doi.org/10.1016/j.ymthe.2021.06.013IF=8.986
The Parkinson’s disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release.
J Med Chem. 2021. DOI: 10.1073/pnas.2006476118IF=9.412
Programmed genome editing by a miniature CRISPR-Cas12f nuclease.
Nature Chemical Biology, 2021. DOI: https://doi.org/10.1038/s41589-021-00868-6.IF=12.587
The immunodominant and neutralization linear epitopes for SARS-CoV-2.
Cell Reports, 2021. DOI: https://doi.org/10.1016/j.celrep.2020.108666.IF=8.109
SCD Inhibition Protects from α-Synuclein- Induced Neurotoxicity But Is Toxic to Early Neuron Cultures.
eNeuro, 2021. DOI: https://doi.org/10.1523/ENEURO.0166-21.2021IF=3.317
Prevalence of Adeno-Associated Virus 3 Capsid Binding and Neutralizing Antibodies in Healthy and Hemophilia B Individuals from India.
Human Gene Therapy, 2021. DOI: https://doi.org/10.1089/hum.2020.258IF=4.51
Eliminating base -editor -induced genome -wide and transcriptome -wide off-target mutations.
Human Gene Therapy, 2021. DOI: https://doi.org/10.1038/s41556-021-00671-4 IF=20.761
Differential development and electrophysiological activity in cultured cortical neurons from the mouse and cynomolgus monkey.
Human Gene Therapy, 2021. DOI: 10.4103/1673-5374.313056. IF=5.135
Development of a one-step RT-ddPCR method to determine the expression and potency of AAV vectors.
Human Gene Therapy, 2021. DOI: https://doi.org/10.1016/j.omtm.2021.05.003.
Promoter CAG is more efficient than hepatocyte targeting TBG for transgene expression via rAAV8 in liver tissues.
Rep. 2022. DOI: 10.3892/mmr.2021.12532
Synthetic immunomodulation with a CRISPR super repressor in vivo[J].
Nature Cell Biology, 2020. DOI: 10.1038/s41556-020-0563-3 IF=20.042
MicroRNA-20b Promotes Cardiac Hypertrophy by the Inhibition of Mitofusin 2-Mediated Inter-organelle Ca 2+ Cross-Talk[J].
Molecular therapy. Nucleic acids, 2020. DOI: https://doi.org/10.1016/j.omtn.2020.01.017 IF=7.032
Adeno Associated Virus D Sequence Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene : Implications in the Development of Adeno Associated Virus Vectors for Modulating Humoral Immune Response[J].
Molecular therapy. Nucleic acids, 2020. DOI: 10.1089/hum.2020.018 IF=4.273
A Whole-Brain Cell-Type Specific Sparse Neuron Labeling Method and Its Application in a Shank3 Autistic Mouse Model[J].
Front Cell Neurosci, 2020. DOI: 10.3389/fncel.2020.00145 IF=3.921
Remdesivir Metabolite GS-441524 Effectively Inhibits SARS-CoV2 Infection in Mouse Models. J Med Chem 2020.
J Med Chem 2020. DOI: 10.1021/acs.jmedchem.0c01929 IF=6.205
Serpina3n is closely associated with fibrotic procession and knockdown ameliorates bleomycin induced pulmonary fibrosis.
Biochem Biophys Res Commun. 2020. DOI: 10.1016/j.bbrc.2020.08.094IF=3.027
Temperature dependence of the SARS-CoV-2 affinity to human ACE2 determines COVID-19 progression and clinical outcome.
CSBJ 2020. DOI: https://doi.org/10.1016/j.csbj.2020.12.005IF=6.018
JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency. nature communications 2020.
DOI: https://doi.org/10.1038/s41467-020-18900-z IF=12.121
Comment on Rapid and efficient in vivo astrocyte -to- neuron conversion with regional identity and connectivity.
2020. bioRxiv DOI: https://doi.org/10.1101/2020.09.02.279273
The immunodominant and neutralization linear epitopes for SARS-CoV-2.
Cell Reports, 2020. DOI: 10.1016/j.celrep.2020.108666
Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vector Implications in Gene Therapy and Genome Editing[J].
Human Gene Therapy, 2020. DOI: 10.1016/j.omtn.2020.03.009 IF=4.273
Neurobiology-Expression Pattern of ALOXE3 in Mouse Brain Suggests Its Relationship with Seizure Susceptibility,
Cellular and Molecular,2020. DOI: https://doi.org/10.1007/s10571-020-00974-4IF=1.72
Intravascular Injections of Adeno associated Viral Vector Serotypes rh10 and PHP.B Transduce Murine Sciatic Nerve Axons[J].
Neuroscience Letter, 2019. DOI: 10.1016/j.neulet.2019.05.010IF=2.274
Anterior cingulate cortex dysfunction underlies social deficits in Shank3 mutant mice[J].
Nature Neuroscience, 2019. DOI: 10.1038/s41593-019-0445-9 IF=20.071
Divergent engagements between adenoassociatedviruses with their cellular receptor AAVR[J].
Nature Communications, 2019. DOI: 10.1038/s41467-019-11668-x IF=12.121
MiR-592 functions as a tumor suppressor in acute myeloid leukemia by targeting ROCK1 and predicts patients’ prognosis[J].
EUR REV MED PHARMACO, 2019. DOI:10.26355/eurrev_201902_17120 IF=3.024
Intravenous injection of AAV-PHP.eB across the blood brain barrier in the adult mouse for central nervous system gene therapy[J].
Oncology and Translational Medicine, 2019.DOI:10.1007/s10330-018-0313-3

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